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Behavioral expression of pain in rats
Zámečník, Jakub ; Vaculín, Šimon (advisor) ; Boukalová, Štěpána (referee)
The aim of this work is to summarize the current knowledge regarding the behavioral expressions of pain in rat. The work is focused on rats, because they are one of the most used laboratory animals, and may experience pain in some experiments. Behavioral expressions of pain were selected, because they are quite easily recognizable and measurable. The reader will be first acquainted with the necessary basics associated with the phenomenon of pain, with its conception in animals, with classification, physiology and for example with the ways in which are in rats experimentally induced pain. Then in the second part, there are shown individual behavioral expressions with examples in which cases were these manifestations observed. So everyone who is interested can learn something about pain in connection with the avoidance reaction, pose, appearance, specific movements of rat, vocalization, changes in eating and drinking, changes in activity, anxiety, cognitive functions and many other expressions. The work can be valuable contribution for all workers with animals and with its character can contribute to animal welfare. Powered by TCPDF (www.tcpdf.org)
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Behavioral expression of pain in rats
Zámečník, Jakub ; Vaculín, Šimon (advisor) ; Boukalová, Štěpána (referee)
The aim of this work is to summarize the current knowledge regarding the behavioral expressions of pain in rat. The work is focused on rats, because they are one of the most used laboratory animals, and may experience pain in some experiments. Behavioral expressions of pain were selected, because they are quite easily recognizable and measurable. The reader will be first acquainted with the necessary basics associated with the phenomenon of pain, with its conception in animals, with classification, physiology and for example with the ways in which are in rats experimentally induced pain. Then in the second part, there are shown individual behavioral expressions with examples in which cases were these manifestations observed. So everyone who is interested can learn something about pain in connection with the avoidance reaction, pose, appearance, specific movements of rat, vocalization, changes in eating and drinking, changes in activity, anxiety, cognitive functions and many other expressions. The work can be valuable contribution for all workers with animals and with its character can contribute to animal welfare. Powered by TCPDF (www.tcpdf.org)
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Methods for measuring pain in animals
Štěrbová, Petra ; Vaculín, Šimon (advisor) ; Nerandžič, Vladimír (referee)
Pain in animals was almost completely overlooked in the last years. It was assumed that animals do not suffer because they are not able to tell it anyway. In a recent time we know that it's not truth and the animals can physically feel pain as we do. This thesis is summarization of the basic knowledge about the pain measurement of animals. However, there are two different approaches to the measurement of pain. The first one is based on the threshold of pain, the another one observes changes in behavior. There have been number of animal models developed in order to pain detection. Exploration of the pain in animals can help us to clarify mechanisms and treatments for serious and chronic neuropathic pain. From an ethical point of view, it's almost impossible to expose a person to serious neuropathic injury for experimental purposes. Therefore, in these cases, the animals are commonly used. And besides this fact, nowadays animals represent a full member of the family for many people, so it is something like moral obligation for us to relieve a pain in animals.
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